Prediction of lipophilicity, solubility and the corresponding pH-dependent profiles and drug absorption
Software suite SLIPPER-2001 can be useful for
chemists, biochemists, ecologists, molecular biologists, medicinal
chemists and pharmacologists.
SLIPPER-2001 (Solubility, LIPophilicity, PERmeability) is used to predict the aqueous solubility, lipophilicity and absorption for a wide range of compounds based on structural similarity and physico-chemical properties of compounds.
With SLIPPER you will be able…
- to predict the octanol/water partition coefficient value ( logD ) at different pH for a single compound or for an entire database containing hundreds thousands compounds
- to predict an aqueous solubility value ( logSw ) at any pH
- to get logD – pH and logSw - pH profiles
- to use both the internal databases SLIPPER and databases in SDF-format
- to save the results in *.doc, *.sdf , *.xls or *.txt formats.
